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During the official shortage, even legitimate telehealth companies like Hims & Hers jumped in by selling compounded semaglutide under an FDA loophole an entirely legal move due to the shortage, but one that highlights how far demand outstripped the normal supply chain

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Keeping a log of symptoms, including when they occur and how severe they are, can help healthcare providers determine the best course of action

A recent metanalysis detected that patients taking GLP-1 RA had a prolonged T 1/2 (the time required for 50% of ingested gastric contents to leave the stomach) of 138 min (confidence interval [CI] 74202 min) vs 95 min (CI 55135 min) in the placebo group, with a pooled mean difference of 36 min ( P 4 h for clear liquids with 10% carbohydrate content in patients taking GLP-1 RAs, we recommend a fasting duration of 8 h for high-calorie liquids